Professor (CHS) - Medical Director for Clinical Laboratories
600 Highland Avenue
Madison, WI 53792-8550
Clinical pathologic correlates in non-Hodgkin lymphoma; Immunomorphometric assessment of potential prognostic biomarkers in non-Hodgkin lymphoma
My research focusses on discovery and validation of pathologic correlates that would help resolve diagnostic and prognostic clinical challenges for patients with non-Hodgkin lymphoma. Specifically, with the help of the Translational Research Initiatives in Pathology Laboratory, we are interested in utilizing automated immunomorphometric assessment of protein expression in tissue microarrays combined with DNA/RNA analysis of corresponding formalin-fixed paraffin-embedded tissue as an approach to translational biomarker discovery and validation.
Hematopathology; Laboratory hematology
Working in conjunction with hematologists to diagnose hematologic disorders is my primary clinical interest. As a part of this, performance characterization of clinical laboratory diagnostics and procedures has been an area of focus.
- Tanimura N, Miller E, Igarashi K, et al. “Mechanism governing heme synthesis reveals a GATA factor/heme circuit that controls differentiation.” EMBO Rep.. 2016;17(2):249-65.
- Nyflot MJ, Kruser TJ, Traynor AM, et al. “Phase 1 trial of bevacizumab with concurrent chemoradiation therapy for squamous cell carcinoma of the head and neck with exploratory functional imaging of tumor hypoxia, proliferation, and perfusion.” Int. J. Radiat. Oncol. Biol. Phys.. 2015;91(5):942-51.
- Imaizumi M, Li-Jessen NYK, Sato Y, Yang DT, Thibeault SL. “Retention of Human-Induced Pluripotent Stem Cells (hiPS) With Injectable HA Hydrogels for Vocal Fold Engineering.” Ann. Otol. Rhinol. Laryngol.. 2017;126(4):304-314.