David Yang

MD

Associate Professor (CHS) - Medical Director for Clinical Laboratories

dtyang@wisc.edu

(608) 265-2095

B4/251B CSC
600 Highland Avenue
Madison, WI 53792-8550

Research Interests

Clinical pathologic correlates in non-Hodgkin lymphoma; Immunomorphometric assessment of potential prognostic biomarkers in non-Hodgkin lymphoma

Detail:

My research focusses on discovery and validation of pathologic correlates that would help resolve diagnostic and prognostic clinical challenges for patients with non-Hodgkin lymphoma. Specifically, with the help of the Translational Research Initiatives in Pathology Laboratory, we are interested in utilizing automated immunomorphometric assessment of protein expression in tissue microarrays combined with DNA/RNA analysis of corresponding formalin-fixed paraffin-embedded tissue as an approach to translational biomarker discovery and validation.

Clinical Interests

Hematopathology; Laboratory hematology

Detail:

Working in conjunction with hematologists to diagnose hematologic disorders is my primary clinical interest. As a part of this, performance characterization of clinical laboratory diagnostics and procedures has been an area of focus.

Selected Publications
  • Tanimura N, Miller E, Igarashi K, et al. “Mechanism governing heme synthesis reveals a GATA factor/heme circuit that controls differentiation.” EMBO Rep.. 2016;17(2):249-65.
  • Nyflot MJ, Kruser TJ, Traynor AM, et al. “Phase 1 trial of bevacizumab with concurrent chemoradiation therapy for squamous cell carcinoma of the head and neck with exploratory functional imaging of tumor hypoxia, proliferation, and perfusion.” Int. J. Radiat. Oncol. Biol. Phys.. 2015;91(5):942-51.
  • Imaizumi M, Li-Jessen NYK, Sato Y, Yang DT, Thibeault SL. “Retention of Human-Induced Pluripotent Stem Cells (hiPS) With Injectable HA Hydrogels for Vocal Fold Engineering.” Ann. Otol. Rhinol. Laryngol.. 2017;126(4):304-314.

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