Catherine Leith

MB, BChir

Professor (CHS), Director of Hematopathology

cleith@uwhealth.org

(608) 263-9031

K4/434 CSC-8550
600 Highland Avenue
Madison, WI 53792-8550

Pager
(608) 265-7000 #8620
Office
K4/434 CSC

Research Interests

Optimizing quality and efficiency of pathology diagnosis while containing costs.
I am interested in improving standard strategies to diagnose and monitor hematologic disorders that maintain diagnostic excellence while containing costs.

Clinical Interests

Hematopathology. Flow cytometry.

I am division chief in hematopathology. In hematopathology, we examine all bone marrows from patients treated at UW hospital. In addition we examine lymph nodes and other tissue specimens from patients with suspected hematopoietic malignancies. Morphologic interpretation is supplemented by immunohistochemistry, flow cytometric studies, cytogenetics, and/or molecular studies as appropriate for each case. We work closely with the clinicians at UW hospital, and meet with pediatric hematology-oncologists and adult hematologists on a weekly basis to review and discuss interesting cases. I also run the flow cytometry laboratory, which is responsible for immunophenotyping of bone marrows and lymph nodes as appropriate, as well as immunodeficiency testing and CD34 analysis among others.

Selected publications
  • Leith C.Multidrug resistance in leukemia.Curr. Opin. Hematol.. 1998;5(4):287-91.
  • Rimsza LM, Viswanatha DS, Winter SS, Leith C, Frost JD, Foucar K. “The presence of CD34+ cell clusters predicts impending relapse in children with acute lymphoblastic leukemia receiving maintenance chemotherapy.Am. J. Clin. Pathol.. 1998;110(3):313-20.
  • Yang DT, Quann PJ, Petrich AM, Leith C, Young KH, Kahl BS. “Use of tissue microarray and automated quantitative analysis for screening and validation of potential biomarkers in mantle cell lymphoma.Appl. Immunohistochem. Mol. Morphol.. 2011;19(1):62-9.